Standard Operating Procedures (SOP)

This document must be downloaded, then viewed and filled out using the web browser view, not in Adobe Acrobat.

Standard Operating Procedures (SOPs) are written instructions, required by OSHA Standard 29 CFR 1910.1450, “Occupational exposure to hazardous chemicals in laboratories”, that document work practices and processes that must be followed when using hazardous chemicals. SOP documentation is required for work involving:

  • Particularly Hazardous Substances (PHS), which include carcinogens, reproductive toxins, and highly/acutely toxic chemicals.  
  • Hazardous biological substances and organisms
  • Novel chemicals of unknown toxicity.

SOPs must be reviewed and approved by EH&S, and in certain circumstances, may necessitate consultation with subject matter experts.  When requested, EH&S will provide assistance in the development of the written SOP.

Current SOPs must be readily accessible for reference in the workplace to all laboratory/facility personnel using the material.

Writing The SOP?

Detailed instructions for writing an SOP can be found in both the Chemical Hygiene Plan and SOP Instructions documents. These instructions are used to complete the general SOP form.

Submission and Approval?

The PI or lab manager must submit the SOP to EH&S. Whenever a PHS is introduced to a lab, or the lab work has concluded, revise the SOP form and send the updated form to EH&S. EH&S may return the SOP with comments or corrections.  Following comments or corrections, any lab staff member who works with or near the substance must be trained in the SOP. The completed SOP must be kept in your lab’s Safety Binder.